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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Expression profiling of Ewing sarcoma cell lines exposed to 5nM Pladienolide B (PlaB) for 24 hours

ABSTRACT: Identification of genes and pathways altered by PlaB, a bacterial natural product that acts as a spliceosome modulator by targeting the SF3b subunit of the spliceosome SKNMC, TC32, TC71, and RD-ES Ewing sarcoma cell lines were treated with 0.1% (v/v) DMSO vehicle or 5nM PlaB for 24 hours. Three samples in each group were analyzed.

ORGANISM(S): Homo sapiens

SUBMITTER: Suntae Kim

PROVIDER: E-GEOD-67548 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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