Whole genome expression microarray analysis in quadriceps of wild-type and NF90-NF45 double transgenic mouse

ABSTRACT: The complex of NF90 and NF45 is known to participate in transcriptional regulation, mRNA stabilization and microRNA biogenesis in vitro. However, the physiological function of the NF90-NF45 complex is still unclear. To elucidate its functions, we generated NF90-NF45 double transgenic (dbTg) mice. Robust expression of NF90 and NF45 was detected in skeletal muscle. As mentioned above, NF90-NF45 complex is involved in regulation of genes via transcription and RNA metabolism. To identify genes regulated by NF90-NF45, we performed comprehensive analyses of mRNA expression in quadriceps of wild-type (WT) and NF90-NF45 dbTg mice. mRNA expression profile in quadriceps comparing WT and NF90-NF45 dbTg mice.

ORGANISM(S): Mus musculus

SUBMITTER: Shuji Sakamoto 

PROVIDER: E-GEOD-67591 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress