Epigenetic determinants of self-renewal in glioblastoma

ABSTRACT: We over-expressed an epigenetic regulator in a glioblastoma (GBM) primary culture from an adult patient. These GBM cells have cancer stem cell phenotypes, as they have self-renewal properties and tumor initiation potential when transplanted in immunocompromised mice. ATAC-seq was performed on cells over-expressing the epigenetic regulator and control cells expressing EGFP. ATAC-Seq on glioblastoma cells that over-express EGFP or an epigenetic regulator.

ORGANISM(S): Homo sapiens

SUBMITTER: Alexander Murison 

PROVIDER: E-GEOD-67633 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress