Transcriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Amol Shetty
PROVIDER: E-GEOD-67688 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Transcriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome.
Bruno Vincent M VM Shetty Amol C AC Yano Junko J Fidel Paul L PL Noverr Mairi C MC Peters Brian M BM
mBio 20150421 2
<h4>Unlabelled</h4>Treatment of vulvovaginal candidiasis (VVC), caused most frequently by Candida albicans, represents a significant unmet clinical need. C. albicans, as both a commensal and a pathogenic organism, has a complex and poorly understood interaction with the vaginal environment. Understanding the complex nature of this relationship is necessary for the development of desperately needed therapies to treat symptomatic infection. Using transcriptome sequencing (RNA-seq), we characterize ...[more]
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