Transcription profiling of mouse HDAC2 knockout myocardium

ABSTRACT: We used microarrays to detail the global programme of gene expression underlying cardiac development by HDAC2 and identified distinct classes of up-regulated and down-regulated genes during this process. Experiment Overall Design: Embryonic heart ventricles were dissected at E17.5 for RNA extraction and hybridization on Affymetrix microarrays. Wild type and HDAC2-deficient littermates were used. Tissue from 2-3 individual animals of identical genotype was pooled for each micro-array.

ORGANISM(S): Mus musculus

SUBMITTER: Jonathan Epstein 

PROVIDER: E-GEOD-6770 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress