Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing

ABSTRACT: We discovered that two mitotic regulators, BuGZ and Bub3, involved in splicing regulation during interphase 8 samples from primary Human foreskin fibroblast cells (HFFs) , 12 samples from TOV21G cells. Control siRNA. BuGZ siRNA or Bub3 siRNA were transfected for 48 h before sample collection. Cells treated with pladienolide B served as positive controls. For each RNAi experiment, we had two biological replicates.

ORGANISM(S): Homo sapiens

SUBMITTER: Yixian Zheng 

PROVIDER: E-GEOD-67770 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress