Omics profiling of 21 novel primary and metastatic colorectal cancer cell lines
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Arnoud Boot
PROVIDER: E-GEOD-67775 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Boot Arnoud A van Eendenburg Jaap J Crobach Stijn S Ruano Dina D Speetjens Frank F Calame Jan J Oosting Jan J Morreau Hans H van Wezel Tom T
Oncotarget 20160301 12
In vitro models are essential to understanding the molecular characteristics of colorectal cancer (CRC) and the testing of therapies for CRC. Many efforts to establish and characterize primary CRC cell lines have been published, most describing a small number of novel cell lines. However, there remains a lack of a large panel of uniformly established and characterized cell lines. To this end we established 20 novel CRC cell lines, of which six were derived from liver metastases. Genetic, genomic ...[more]
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