Fibroblasts from genital and extragenital regions of 46,XY individuals

ABSTRACT: This dataset contains fibroblasts from different genital and extragenital regions, mostly from 46,XY individuals. Due to proven androgen receptor gene mutations, several individuals have varying degrees of undervirilization of the external genitalia ranging from complete androgen insensitivity syndrome (CAIS) to partial androgen insensitivity syndrome (PAIS). CAIS is a completely female person despite a 46,XY karyotype. AIS-3 individuals have ambigous external genitalia. AIS-4 means predominantly female (clitoral enlargement), AIS-2 means predominantly male (hypospadias). It is important for this experiment set, that it contains data from 3 differet independent datasets that are not directly cmparable with each other. This is because of different reference RNAs and different glass slides.

ORGANISM(S): Homo sapiens

SUBMITTER: Paul-Martin Holterhus 

PROVIDER: E-GEOD-6796 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress