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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptome characterization of social stressed C57B6 mice exhibiting PTSD like features

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: seid muhie

PROVIDER: E-GEOD-68077 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Brain transcriptome profiles in mouse model simulating features of post-traumatic stress disorder.

Muhie Seid S Gautam Aarti A Meyerhoff James J Chakraborty Nabarun N Hammamieh Rasha R Jett Marti M

Molecular brain 20150228

<h4>Background</h4>Social-stress mouse model, based on the resident-intruder paradigm was used to simulate features of human post-traumatic stress disorder (PTSD). The model involved exposure of an intruder (subject) mouse to a resident aggressor mouse followed by exposure to trauma reminders with rest periods. C57BL/6 mice exposed to SJL aggressor mice exhibited behaviors suggested as PTSD-in-mouse phenotypes: intermittent freezing, reduced locomotion, avoidance of the aggressor-associated cue ...[more]

PMID: 25888136

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Transcriptome profiling of spleen, blood and hemi-brain of social stressed C57B6 mice exhibiting PTSD like features

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