Gene predictors of response to bendamustine in CLL cells

ABSTRACT: Bendamustine is a commonly-used drug to treat CLL patients. Because drug-responses among the patients are heterogeneous, we wanted to find candidate genes to predict sensitivity to the compound We used microarrays to find genes whose expression correlates with the in vitro induced-cytotoxcity by a 24-hour incubation with bendamustine 25 µm RNA was extracted from CD19+ tumoral cells from 38 PBMCs of CLL cases

ORGANISM(S): Homo sapiens

SUBMITTER: DOLORS COLOMER 

PROVIDER: E-GEOD-68163 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress