Gene Expression Profiling of Chronically Inflamed FFPE Placental Tissue

ABSTRACT: The aim of this research was to explore gene expression changes in chronically inflammed placental tissue This study compared FFPE tissue with and without chronic placental inflammation, manifested as overlapping chronic chorioamnionitis, chronic villitis of unknown etiology, and chronic deciduitis. RNA expression profiling was conducted on formalin fixed, paraffin embedded placental tissue using Illumina microarrays. To further explore and validate gene expression findings, we conducted immunohistochemical assessment of protein level expression.

ORGANISM(S): Homo sapiens

SUBMITTER: Jefferson Terry 

PROVIDER: E-GEOD-68474 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress