Comparative genomics of Steinernema reveals deeply conserved regulatory networks in nematodes

ABSTRACT: Parasitism is a major ecological niche for a variety of nematodes. Multiple nematode lineages have specialized as pathogens, including deadly parasites of insects that are used in biological control. We have sequenced and analyzed the draft genomes and transcriptomes of the entomopathogenic nematode Steinernema carpocapsae and four congeners (S. scapterisci, S. monticolum, S. feltiae, S. glaseri) distantly related to Caenorhabditis elegans. We used these genomes to establish phylogenetic relationships, explore gene conservation across species, identify genes uniquely expanded in insect parasites, and to identify conserved non-coding regulatory motifs that influence similar biological processes. Protein domain analysis of these genomes reveals a striking expansion of numerous putative paras

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Marissa Macchietto 

PROVIDER: E-GEOD-68588 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress