Dataset Information
RNA-seq of postnatal day 0 (P0) wild-type and Satb2-/- cortices
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Bin Chen
PROVIDER: E-GEOD-68911 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex.
Proceedings of the National Academy of Sciences of the United States of America 20150831 37
Generation of distinct cortical projection neuron subtypes during development relies in part on repression of alternative neuron identities. It was reported that the special AT-rich sequence-binding protein 2 (Satb2) is required for proper development of callosal neuron identity and represses expression of genes that are essential for subcerebral axon development. Surprisingly, Satb2 has recently been shown to be necessary for subcerebral axon development. Here, we unravel a previously unidentif ...[more]
