The role of PCNA ubiquitylation during unperturbed genome replication in S.pombe

ABSTRACT: To establish if PCNA ubiquitylation affects the DNA replication kinetics of specific loci, we compared rates of DNA replication across the genome between rad18+ and rad18-delta cells using the BrdU-IP sequencing method. We mapped BrdU-incorporation at 300-bp resolution and subsequent informatics analysis was performed to generate datasets of replication kinetics.

ORGANISM(S): Schizosaccharomyces pombe

SUBMITTER: Yasukazu Daigaku 

PROVIDER: E-GEOD-70033 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress