Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of mouse gnotobiotic ileum, listeria infection series

ABSTRACT: Ileal profiles from gnotobiotic mice mono-associated with Listeria species or B. thetaiotaomicron. Samples were derived from 72h colonizations of Fabpi-hEcad transgenic B6 mice fed a standard-chow polysaccharide rich (PR) diet. Experiment Overall Design: Total RNA was prepared from ileum of 72 hour mono-associated gnotobiotic male mice, biotin labeled, and hybridized to 430 2.0 GeneChips.

ORGANISM(S): Mus musculus

SUBMITTER: Justin Sonnenburg 

PROVIDER: E-GEOD-7013 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Functional genomic studies of the intestinal response to a foodborne enteropathogen in a humanized gnotobiotic mouse model.

Lecuit Marc M   Sonnenburg Justin L JL   Cossart Pascale P   Gordon Jeffrey I JI  

The Journal of biological chemistry 20070327 20

Members of the genus Listeria provide a model for defining host responses to invasive foodborne enteropathogens. Active translocation of Listeria monocytogenes across the gut epithelial barrier is mediated by interaction of bacterial internalin (InlA) and its species-specific host receptor, E-cadherin, whereas translocation across Peyer's patches through M-cells is InlA-independent. To define microbial determinants and molecular correlates of the host response to translocation via these two rout  ...[more]

Similar Datasets

Unknown Gnotobiotic mouse ileum; Listeria infection series
2007-04-23 | GSE7013 | GEO
Unknown Gnotobiotic mouse cecal epithelium; B.thetaiotaomicron-B. longum mono- versus bi-association, PR chow, NMRI
2007-01-01 | GSE5870 | GEO
Transcriptomics Gnotobiotic mouse cecal epithelium; B.thetaiotaomicron-B. longum mono- versus bi-association, PR chow, NMRI
2010-10-08 | E-GEOD-5870 | biostudies-arrayexpress
Unknown B.thetaiotaomicron mono-association versus B. thetaiotaomicron co-colonization with B. longum, PR chow, B6
2007-01-01 | GSE5866 | GEO
Transcriptomics B.thetaiotaomicron mono-association versus B. thetaiotaomicron co-colonization with B. longum, PR chow, B6
2010-07-01 | E-GEOD-5866 | biostudies-arrayexpress
Transcriptomics B.thetaiotaomicron mono-association versus B. thetaiotaomicron co-colonization with B. animalis or L. casei, PR chow, B6
2010-07-01 | E-GEOD-5867 | biostudies-arrayexpress
Unknown B.thetaiotaomicron mono-association versus B. thetaiotaomicron co-colonization with B. animalis or L. casei, PR chow, B6
2007-01-01 | GSE5867 | GEO
Unknown B.thetaiotaomicron or B. longum mono-association versus B. thetaiotaomicron/B. longum co-colonization, PR chow, NMRI
2007-01-01 | GSE5865 | GEO
Transcriptomics B.thetaiotaomicron or B. longum mono-association versus B. thetaiotaomicron/B. longum co-colonization, PR chow, NMRI
2010-07-01 | E-GEOD-5865 | biostudies-arrayexpress
Unknown Transcriptional profiling of Salmonella typhimurium in the ceca of gnotobiotic mice
2013-07-23 | GSE49076 | GEO