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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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MiRNA Expression data from human osteosarcoma (OS)

ABSTRACT: To explore possible oncogenic factors in OS, we used a microarray-based approach to profile changes in the expression of miRNAs in five OS cell lines and human mesenchymal stem cells (hMSCs). We used a microarray-based approach to profile in the miRNA expression of OS Human OS cell lines were analyzed with genome-wide expression arrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Masanori Kawano

PROVIDER: E-GEOD-70367 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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mRNA Expression data from human osteosarcoma (OS)

Project description:To explore possible oncogenic factors in OS, we used a microarray-based approach to profile changes in the expression of mRNAs in five OS cell lines and human mesenchymal stem cells (hMSCs). We used a microarray-based approach to profile the mRNA expression of OS Human OS cell lines were analyzed with genome-wide expression arrays.

2015-07-01 | E-GEOD-70414 | biostudies-arrayexpress

mRNA and miRNA expression data from human osteosarcoma (OS)

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-07-01 | E-GEOD-70415 | biostudies-arrayexpress

microRNA Expression data from human Ewing's sarcoma (ES)

Project description:To explore possible oncogenic factors in ES, we used a microarray-based approach to profile changes in the expression of miRNAs in five ES cell lines and human mesenchymal stem cells (hMSCs). We used a microarray-based approach to profilein the mRNA expression of ES Human ES cell lines were analyzed with genome-wide expression arrays.

2015-07-14 | E-GEOD-70825 | biostudies-arrayexpress

mRNA Expression data from human Ewing's sarcoma (ES)

Project description:To explore possible oncogenic factors in ES, we used a microarray-based approach to profile changes in the expression of mRNAs in five ES cell lines and human mesenchymal stem cells (hMSCs). We used a microarray-based approach to profilein the mRNA expression of ES Human ES cell lines were analyzed with genome-wide expression arrays.

2015-07-14 | E-GEOD-70826 | biostudies-arrayexpress

mRNA Expression data from human osteosarcoma (OS)

2015-07-01 | GSE70414 | GEO

miRNA Expression data from human osteosarcoma (OS)

Project description:To explore possible oncogenic factors in OS, we used a microarray-based approach to profile changes in the expression of miRNAs in five OS cell lines and human mesenchymal stem cells (hMSCs). We used a microarray-based approach to profile in the miRNA expression of OS

2015-07-01 | GSE70367 | GEO

mRNA and miRNA expression data from human Ewing's sarcoma (ES)

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-07-14 | E-GEOD-70827 | biostudies-arrayexpress

Transcription profiling of human osteosarcoma Sa OS cells vs reference RNA of human osteosarcoma U-2 OS cells

Project description:Osteosarcoma (OS) is a common primary bone malignancy that is characterized by high degree of aneuploidy, gene amplification, and multiple unbalanced chromosomal rearrangements. The human osteosarcoma U-2 OS and Sa OS cells lines have been generated more than three decades ago and are used in a wide spectrum of biomedical research. Nevertheless, and despite scattered information about their genetic context, no comprehensive comparative study of their transcriptome profile has been reported to date. The aim of this study was to elucidate common molecular characteristics of the two cell lines as well as differences in their expression profile. Thus the genome wide gene expression profile of the Sa OS cells was compared with reference RNA of U-2 OS cells. These results may provide the basis for future studies and illuminate the molecular differences of the two widely used cell lines.

2009-09-21 | E-MEXP-1897 | biostudies-arrayexpress

Burkholderia pseudomallei OS strain:OS

Project description:Burkholderia pseudomallei OS strain:OS Genome sequencing and assembly

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Changes in gene expression in HOS and U2-OS cell lines after exposure to 600 Î¼g/mL OGE

Project description:Osteosarcoma (Osteosarcoma) is a type of bone cancer. Eighty percent of this tumor will be metastatic to the lungs or liver, and as a result, patients generally need chemotherapy to improve survival possibility. Recently, anti-tumor activity has been reported in Ocimum gratissimum aqueous extract (OGE), which has been the focus of recent extensive studies on therapeutic strategies due to its antioxidant properties. We used microarrays to identify potential and novel target genes responsive to the anticancer effect in OGE treatment in osteosarcoma cells, We performed pharmacogenomics analyses for the effect of OGE on human osteosarcoma U2-OS and HOS cell growth. Cell viability, Western blot and flow cytometry analysis were performed before performing pharmacogenomics analyses for the effect of OGE on human osteosarcoma U2-OS and HOS cell growth, including cDNA microarray and RT-PCR assays.

2013-06-26 | E-GEOD-48281 | biostudies-arrayexpress

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