Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

9 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide bisulfite sequencing reveals enhancer as main target of DNA methyltion in neural conversion [Bisulfite-seq]

ABSTRACT: Genome-wide bisulfite sequencing and corresponding transcriptome are analyzed together to seek for methylation target during neural differentiation H1 human embryonic stem cells are able to differentiated into neural stem cells with induction of compound C in 72h. We extracted genomic DNA from 0, 24, 48h samples during induction and measured their DNA methylation level by BS-seq.

ORGANISM(S): Homo sapiens

SUBMITTER: Gang Liu

PROVIDER: E-GEOD-70997 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Sequential DNA methylation and gene expression during human embryonic stem cell inducing into neural progenitor cell

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-07-16 | E-GEOD-70998 | biostudies-arrayexpress

High-throughput Illumina sequencing of bisulfite transformed genomic DNA from Arabidopsis thaliana wild-type, msh1 mutant and MSH1-epiF3 lines

Project description:Arabidopsis msh1 mutants display developmental reprogramming (dr) phenotypes, include reduction in growth, enhanced branching, and delayed maturation and flowering time. MSH1-epi lines were derived by crossing MSH-dr lines with Col-0 wild type, followed by selection for homozygous MSH1/MSH1 F2 plants and serial self-pollination. MSH1-epiF3 plants displayed phenotypic variation in plant growth, showing enhanced growth, larger rosette diameter, thicker floral stems and earlier flowering time. We carried bisulfite sequencing and uncover the methylome changes accompany the heritable MSH1-epi phenotypes that condition dramatic variation in plant growth. 3 samples examined: wild type, Msh1-epiF3, msh1 mutant

2014-01-01 | E-GEOD-36783 | biostudies-arrayexpress

Reduced representation bisulfite sequencing data of mouse genome

Project description:RRBS was used to analyse global imprinting gene methylation pattern of offspring from the in vitro derived spermatids like cells and normal control Global imprinting gene methylation pattern comparision of two offspring (one male and one female) from the in vitro derived spermatids like cells and two normal control mice (one male and one female)

2016-02-26 | E-GEOD-76238 | biostudies-arrayexpress

Bisulfite-seq of synovial biopsies from rheumatoid arthritis patients

Project description:Synovial biopsies from rheumatoid arthritis patients were obtained and profiled using bisulfite-seq for whole-genome DNA methylation. Patients were stratified according to the number of swollen joints they had (SJC, swollen joint count) and divided in three groups for the differential expression analysis: None (SJC = 0), Low (1<= SJC <= 8), High (SJC > 8).

2021-04-26 | E-MTAB-6638 | biostudies-arrayexpress

modENCODE RNA-Seq of Drosophila cell lines Kc167, CME_W1_Cl.8+, S2-DRSC and ML-DmBG3-c2

Project description:Deep Sequencing of mRNA from the Drosophila melanogaster cell lines Kc167, CME_W1_Cl.8+, S2-DRSC and ML-DmBG3-c2. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Analysis of poly(A)+ RNA from 2 biological replicates of Kc167, CME_W1_Cl.8+, S2-DRSC and ML-DmBG3-c2 cell lines.

2009-04-08 | E-GEOD-15596 | biostudies-arrayexpress

ChIP-chip of Drosophila Polycomb group proteins Asx and Calypso (PR-DUB) in larvae

Project description:Analysis of binding profile of the Polycomb group proteins Calypso and Asx (PR-DUB) in Drosophila melanogaster larvae.

2010-05-03 | E-TABM-908 | biostudies-arrayexpress

ChIP-chip of Drosophila polycomb group protein Ph and of GlcNAc in larvae

Project description:Analysis of binding profile of the Polycomb group protein Ph and of GlcNAc sites in Drosophila melanogaster larvae. <br><br>Note some of the protocols for this experiment were changed in May 2010.

2010-05-05 | E-TABM-697 | biostudies-arrayexpress

ChIP-chip by tiling array of Drosophila Polycomb group protein Sce/Ring in larvae

Project description:Analysis of binding profile of the Polycomb group protein Sce/Ring in Drosophila melanogaster larvae.

2011-04-03 | E-TABM-988 | biostudies-arrayexpress

ChIP-chip of Drosophila Polycomb group proteins Pho and dSfmbt (PhoRC) in embryos and larvae

Project description:Analysis of binding profile of the Polycomb group proteins Pho and dSfmbt (PhoRC complex) in Drosophila melanogster at two developmental stages (embryos and larvae).

2008-11-06 | E-TABM-525 | biostudies-arrayexpress

Effect of hypoxia on Mycobacterium tuberculosis-host phagocyte interactions

Project description:Mtb appears to have developed specialized biomolecular infrastructure to survive and persist within granulomas, where it is subjected to a diverse set of stress conditions. One of these stress conditions is hypoxia. We hypothesized that host cell response is radically altered with hypoxia stressed Mtb and designed in-vitro experiments to study this phenomenon. Hypoxia-stressed as well as aerobically grown Mtb were used to infect rhesus macaque bone marrow derived macrophages (Rh-BMDMs) and the host global transcriptional response compared. Using 4 x44 k Agilent arrays specific for rhesus macaque genome, we tested in biological duplicate the effect of aerogically grown Mtb on rhesus macaque BMDMs and compared this to the corresponding effect of the hypoxia-conditioned Mtb on rhesus macaque BMDMs

2013-05-22 | E-GEOD-47163 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data