SpdR regulon

ABSTRACT: As bacterial cells enter stationary phase, they adjust their growth rate to comply with nutrient restriction and acquire increased resistance to several stresses. These events are regulated by controlling gene expression at this phase, changing the mode of exponential growth into that of growth arrest, and increasing the expression of proteins involved in stress resistance. The two-component system SpdR/SpdS is required for the activation of transcription of the Caulobacter crescentus cspD gene at the onset of stationary phase. A Global transcriptional analysis at early stationary phase of a spdR null mutant strain compared to the wild type strain was carried out by DNA microarray. Twenty-three genes showed at least twofold decreased expression in the spdR deletion mutant strain relative t

ORGANISM(S): Caulobacter crescentus NA1000

SUBMITTER: Rogerio Lourenco 

PROVIDER: E-GEOD-71337 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress