Characterization of t(15;21) translocations in myeloid disorders

ABSTRACT: We report on two novel t(15;21) alterations [t(15;21)(q24;q22) and t(15;21)(q21;q22)], which led to concurrent disruption of RUNX1 and two translocation partner genes encoding for transcription factors (SIN3A, TCF12) Examination of four different patients with myeloid disorders. 2 out of 4 have been analyzed by means RNAseq

ORGANISM(S): Homo sapiens

SUBMITTER: Alberto L'Abbate 

PROVIDER: E-GEOD-71551 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress