Transcriptome bioinformatical analysis of vertebrate stages of Schistosoma japonicum reveals alternative splicing events

ABSTRACT: Alternative splicing is a molecular process that contributes greatly to the diversification of proteome and to gene functions. Understanding the mechanisms of stage-specific alternative splicing can provide a better understanding of the development of eukaryotes and the functions of different genes. Schistosoma japonicum is an infectious blood-dwelling trematode with a complex lifecycle that causes the tropical disease schistosomiasis. In this study, we analyzed the transcriptome of Schistosoma japonicum to discover alternative splicing events in this parasite, by applying RNA-seq to cDNA library of adults and schistosomula. Results were validated by RT-PCR and sequencing. We found 11,623 alternative splicing events among 7,099 protein encoding genes and average proportion of alternative s

ORGANISM(S): Schistosoma japonicum

SUBMITTER: Xinye Wang 

PROVIDER: E-GEOD-71722 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress