Inhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin [ChIP-Seq]

ABSTRACT: Examine the distribution of KDM1A and the histone H3K4me2 mark on chromatin following treatment with two distinct classes of KDM1A inhibitors - an irreversible inhibitor (RN-1) and a reversible inhibitor (GSK690) 15 samples total from two treated cell lines - 9 from Kasumi-1 and 6 from SKNO-1. Controls included were input DNA isolated from the treated cells.

ORGANISM(S): Homo sapiens

SUBMITTER: Barbara Bryant 

PROVIDER: E-GEOD-71739 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress