Comparison of gene expression data between wild-type and DM1-affected Neural Precursors Cells (NPC)

ABSTRACT: Analysis of genes that were differentially expressed in mutant VUB03_DM1 as compared to controls VUB01 and SA01 Neural Precursor cells Embryonic stem (ES) cell lines provide, theoretically, unlimited access to any needed amount of any specific cell phenotype of an organism, due to their unique capacities at indefinite self-renewal and pluripotency (Smith 2001; Trounson 2006). These properties allow using the progeny of ES cell lines to model human pathologies (Martinat, Shendelman et al. 2004; Lerou and Daley 2005; Ben-Nun and Benvenisty 2006). In particular, human ES cell lines derived from embryos characterized as gene-carriers following pre-implantation genetic diagnosis (PGD) for any one of major monogenic diseases (Pickering, Minger et al. 2005; Mateizel, De Temmerman et al. 2006) ma

ORGANISM(S): Homo sapiens

SUBMITTER: Genevieve PIETU 

PROVIDER: E-GEOD-7178 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress