Effect of a diet enriched with omega-6 and omega-3 fatty acids on the pig liver transcriptome

ABSTRACT: The optimal ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) is important for keeping homeostasis of biological processes and metabolism, yet the underlying biological mechanism is poorly understood. The objective of this study was to identify changes in the pig liver transcriptome induced by a diet enriched with omega-6 and omega-3 fatty acids, and to characterize the biological mechanisms related to PUFA metabolism. Polish Landrace pigs (n =12) were fed diet enriched with linoleic acid (LA, omega-6) and alpha-linolenic acid (ALA, omega-3 family) or standard diet as a control. The fatty acids profiling was assayed in order to verify how feeding influenced the fatty acids content in liver, and subsequently next-generation sequencing (NGS) was used to identify differentially

ORGANISM(S): Sus scrofa

SUBMITTER: Agnieszka Szostak 

PROVIDER: E-GEOD-72123 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress