Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Expression data of CNS T cells during EAE


ABSTRACT: In the absence of NR4A2 in T cells mice do not develop early acute EAE, but only a late chronic disease. We examined the mechanism by which NR4A2 can control the pathogencity of T cells in CNS autoimmune disease. To determine how NR4A2 is involved is involved in T cell pathology, we examined expression profiles of T cells during early and late diease in the presence or genetic CD4-specific absence of NR4A2. T cells infiltrating CNS tissues were isolated at peal acute EAE (D18) or during late,chronic EAE (D32). RNA expression was then analysed by genechip to determine the influence of NR4A2 in T cells on these disease stages

ORGANISM(S): Mus musculus

SUBMITTER: Shinji Oki 

PROVIDER: E-GEOD-72301 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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