Gene expression data from wild-type (WT) and ribbon (rib) mutant Drosophila mid through late stage embryos

ABSTRACT: Transcription factors, which regulate the spatiotemporal patterns of gene expression during organogenesis, often regulate multiple aspects of tissue morphogenesis, including cell-type specification, cell proliferation, cell death, cell polarity, cell shape, cell arrangement and cell migration. In this work, we describe a distinct role for Ribbon (Rib) in controlling cell shape changes during elongation of the Drosophila salivary gland (SG). Notably, the morphogenetic changes in rib mutants occurred without effects on general SG cell attributes such as specification, proliferation and apoptosis. Moreover, the abnormal cell/organ shape in rib mutants occurred without compromising epithelial-specific morphological attributes such as apicobasal polarity and junctional integrity. To identify th

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Deborah Andrew 

PROVIDER: E-GEOD-72598 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress