Toxicogenomics on mice liver of coumarins from Calophyllum brasiliense

ABSTRACT: A toxicogenomic analysis from liver of different pharmacological active coumarins (mammea A/BA+A/BB 3:1 and soulatrolide ) was performed on mice treated (20mg/kg/daily) for a whole week to evaluate if such compounds possess or could develop a hazardous profile on liver. In this dataset, we include the expression data obtained from dissected liver mouse treated with active coumarins (obtained from Calophyllum brasiliense) and control (SSI) for a whole week. Livers from 4 animals per treatment and control were subjected to RNA extraction. These data showed 46 genes up and 72 downregulated genes for mammea coumarins and 665 up and 1077 downregulated genes . Expression data from liver of mice treated with different coumarins (mammea and soulatrolide) from Calophyllum brasiliense 12 Total sam

ORGANISM(S): Mus musculus

SUBMITTER: Juan Gomez-Verjan 

PROVIDER: E-GEOD-72755 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress