Methylation interactions in Arabidopsis hybrids require RNA-directed DNA methylation and are influenced by genetic variation

ABSTRACT: DNA methylation is a conserved epigenetic mark in plants and many animals. How parental alleles interact in progeny to influence the epigenome is poorly understood. We analyzed the DNA methylomes of Arabidopsis Col and C24 ecotypes, and their hybrid progeny. Hy- brids displayed nonadditive DNA methylation levels, termed meth- ylation interactions, throughout the genome. Approximately 2,500 methylation interactions occurred at regions where parental DNA methylation levels are similar, whereas almost 1,000 were at differ- entially methylated regions in parents. Methylation interactions were characterized by an abundance of 24-nt small interfering RNAs. Furthermore, dysfunction of the RNA-directed DNA methylation pathway abolished methylation interactions but did not affect the increased biom

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Yanqiang Li 

PROVIDER: E-GEOD-72993 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress