Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Pascal Martin
PROVIDER: E-GEOD-73290 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Amino acids 20160513 9
Alterations in NO availability and signaling play a pivotal role at early stages of the metabolic syndrome (MetSynd). We hypothesized that dietary α-linolenic acid (ALA, 18:3 n-3) favors NO availability by modulating amino acid metabolism, with a specific impact on the arginine-NO pathway. Mice were fed a hyperlipidic diet (285 g lipid/kg, 51.1 % energy), rich in either saturated fatty acids (SFA, provided by palm oil, PALM group) or ALA (provided by linseed oil, LIN group). We measured whole-bo ...[more]