Identification of novel biomarkers associated with poor patient outcome in invasive breast carcinoma

ABSTRACT: Breast carcinoma (BC) is the leading cause of death in women worldwide, making up 23% of all cancers in women, with 1.38 million new cases worldwide annually and responsible for 460,000 deaths. Despite the significant advances in the identification of molecular markers and different modalities of treatment in primary BC, the ability to predict the metastatic behavior in breast cancer is still limited. The purpose of this study was to help identify novel molecular markers associated with clinical outcome in a cohort of Brazilian BC patients. We generated global gene expression profiles from 24 patients with invasive ductal BC followed for ≥ 5-years, including 15 samples from patients classified as presenting good prognosis based on traditional markers and clinical criteria and 9 patients

ORGANISM(S): Homo sapiens

SUBMITTER: Eduardo Reis 

PROVIDER: E-GEOD-73383 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress