Impact of Verteporfin on HCC cells

ABSTRACT: Together with TEAD4 the Hippo pathway effector YAP stimulates chromosomal instability. Verteporfin is known to disrupt the physical YAP/TEAD interaction and tehrefore might prevent from chromosomal instability in liver cancer. Immortalized HCC cell line hepG2 is treated with Verteporfin for 24 hours.

ORGANISM(S): Homo sapiens

SUBMITTER: Carsten Sticht 

PROVIDER: E-GEOD-73396 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress