Sec66â?? RNAseq
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Madelaine Gogol
PROVIDER: E-GEOD-73681 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Sec66-Dependent Regulation of Yeast Spindle-Pole Body Duplication Through Pom152.
Katta Santharam S SS Chen Jingjing J Gardner Jennifer M JM Friederichs Jennifer M JM Smith Sarah E SE Gogol Madelaine M Unruh Jay R JR Slaughter Brian D BD Jaspersen Sue L SL
Genetics 20151028 4
In closed mitotic systems such as Saccharomyces cerevisiae, the nuclear envelope (NE) does not break down during mitosis, so microtubule-organizing centers such as the spindle-pole body (SPB) must be inserted into the NE to facilitate bipolar spindle formation and chromosome segregation. The mechanism of SPB insertion has been linked to NE insertion of nuclear pore complexes (NPCs) through a series of genetic and physical interactions between NPCs and SPB components. To identify new genes involv ...[more]
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