Identification of Predictive Gene Markers for Multipotent Stromal Cell Proliferation [RT-PCR]

ABSTRACT: Multipotent stromal cells (MSCs) are known for their distinctive ability to differentiate into different cell lineages such as adipocytes, chondrocytes and osteocytes. They can be isolated from numerous tissue sources including bone marrow, adipose tissue, skeletal muscle and others. Because of their differentiation potential and their secretion of growth factors, MSCs are believed to have an inherent quality of regeneration and immune suppression, which are considered advantageous in treating multiple disorders such as graft-versus-host disease. Since the number of MSCs derived from a tissue source is low, cellular expansion is necessary to obtain sufficient numbers for a desired cell therapy. However, after several rounds of passaging, our previous results have shown that MSCs exhibi

ORGANISM(S): Homo sapiens

SUBMITTER: Raj Puri 

PROVIDER: E-GEOD-74203 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress