Oocyte-expressed Yes-associated Protein (YAP) is a Key Activator of the Early Zygotic Genome in Mouse

ABSTRACT: We generated maternal and paternal mouse models with Yap1-deletion, and elucidated the function of maternal YAP in zygotic genome activation. RNA sequencing with 2 WT oocyte samples at GV stage, 2 YAP-/- oocyte samples at GV stage, 1 WT embryo samples at 4cell stage, 1 YAP-/- embryo samples at at 4-cell stage.

ORGANISM(S): Mus musculus

SUBMITTER: yujiao dang 

PROVIDER: E-GEOD-74344 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress