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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Adult-induced cardiac-specific knockout of Parkin provokes minimal transcriptional effect

ABSTRACT: Adult mice bearing homozygous floxed Parkin alleles (PMIDs 15249681, 21376232; T M Dawson), with or without the Myh6-driven MERCreMER transgene, were administered tamoxifen at 6-10 wks of age. Tissues were obtained from euthanized mice 9-10 weeks after tamoxifen induction. 6 floxed, non-Cre (noninduced) mouse hearts; 6 floxed, MERCreMer, adult-induced, Parkin knockout mouse hearts

ORGANISM(S): Mus musculus

SUBMITTER: Scot Matkovich

PROVIDER: E-GEOD-74518 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Adult-induced cardiac-specific knockout of Parkin provokes minimal transcriptional effect

Project description:Adult mice bearing homozygous floxed Parkin alleles (PMIDs 15249681, 21376232; T M Dawson), with or without the Myh6-driven MERCreMER transgene, were administered tamoxifen at 6-10 wks of age. Tissues were obtained from euthanized mice 9-10 weeks after tamoxifen induction.

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