RNA-seq analysis of IMQ-treated wt and Trex2-/- skin

ABSTRACT: TREX2 is a keratinocyte specific 3’-deoxyribonuclease that participates in the maintenance of skin homeostasis upon damage. This transcriptome analysis identified multiple genes and pathways deregulated by TREX2 loss in the IMQ-induced psoriasis-like model in mouse skin. mRNA sequencing of 5 biological replicates of skin from wild-type mice treated with Imiquimod and 6 of Trex2 knockout mice treated with Imiquimod

ORGANISM(S): Mus musculus

SUBMITTER: Eduard Casas 

PROVIDER: E-GEOD-74528 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress