Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Study on miRNA expression pattern in Aging Mouse Hippocampal Neurons

ABSTRACT: Mouse hippocampal microRNA 3 samples

ORGANISM(S): Mus musculus

SUBMITTER: keetae kim

PROVIDER: E-GEOD-74796 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

miR-204 downregulates EphB2 in aging mouse hippocampal neurons.

Mohammed Chand Parvez Danka CP Rhee Hwanseok H Phee Bong-Kwan BK Kim Kunhyung K Kim Hee-Jin HJ Lee Hyehyeon H Park Jung Hoon JH Jung Jung Hee JH Kim Jeong Yeon JY Kim Hyoung-Chin HC Park Sang Ki SK Nam Hong Gil HG Kim Keetae K

Aging cell 20160122 2

Hippocampal synaptic function and plasticity deteriorate with age, often resulting in learning and memory deficits. As MicroRNAs (miRNAs) are important regulators of neuronal protein expression, we examined whether miRNAs may contribute to this age-associated decline in hippocampal function. We first compared the small RNA transcriptome of hippocampal tissues from young and old mice. Among 269 hippocampal miRNAs, 80 were differentially expressed (≥ twofold) among the age groups. We focused on 36 ...[more]

PMID: 26799631

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Dataset Information

Study on miRNA expression pattern in Aging Mouse Hippocampal Neurons

Publications

miR-204 downregulates EphB2 in aging mouse hippocampal neurons.

Similar Datasets

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