H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [Ring1a-1b_RNASeq]

ABSTRACT: The goal of this study is to understand the genome-wide alterations in chromatin landscapy induced by a histone mutation (H3.3 K36M) derived from chondroblastomas Examination of the transcriptome changes of Ring1a and Ring1b knockdown in mouse mesenchymal progenitor cells

ORGANISM(S): Mus musculus

SUBMITTER: Peter Lewis 

PROVIDER: E-GEOD-75854 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress