Rapid evolutionary adaptation to growth on an ‘unfamiliar’ carbon source

ABSTRACT: Cells constantly adapt to changes in their environment. In the majority of cases, the environment shifts between conditions that were previously encountered during the course of evolution, thus enabling evolutionary-programmed responses. In rare cases, however, cells may encounter a new environment to which a novel response is required. To characterize the first steps in adaptation to a novel condition, we studied budding yeast growth on xylulose, a sugar that is very rarely found in the wild. We previously reported that growth on xylulose induces the expression of amino-acid biosynthesis genes, in multiple natural yeast isolates. This induction occurs despite the presence of amino acids in the growth medium and is a unique response to xylulose, not triggered by any of the naturally availa

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Zvi Tamari 

PROVIDER: E-GEOD-76077 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress