Ontology highlight
ABSTRACT:
ORGANISM(S): Ovis aries
SUBMITTER: Charles Wood
PROVIDER: E-GEOD-76110 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Physiological reports 20160331 6
Transient hypoxia in pregnancy stimulates a physiological reflex response that redistributes blood flow and defends oxygen delivery to the fetal brain. We designed the present experiment to test the hypotheses that transient hypoxia produces damage of the cerebral cortex and that ketamine, an antagonist ofNMDAreceptors and a known anti-inflammatory agent, reduces the damage. Late gestation, chronically catheterized fetal sheep were subjected to a 30-min period of ventilatory hypoxia that decreas ...[more]