Transcription profiling of mouse double negative thymocytes

ABSTRACT: In order to understand the molecular mechanisms of DN thymocyte development, it may be also of use to clarify how these developmental processes are regulated in terms of their entire gene expression, to which cell differentiation is ultimately ascribed. In the current study, we approached this issue by investigating gene expression profiles in discrete subsets of DN thymocytes under development, in which DN2, DN3, and DN4 thymocytes were sorted and subjected to expression profiling analysis with high-density oligonucleotide microarrays. Experiment Overall Design: The DN2, DN3, and DN4 populations were FACS-sorted from DN thymocytes harvested from four C57BL/6 mice and analyzed by Affymetrix® Mouse Genome 430 2.0 Array® for gene expression. Four independent experiments were performed

ORGANISM(S): Mus musculus

SUBMITTER: Masahito Kawazu 

PROVIDER: E-GEOD-7784 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress