Comparison of gene expression in M. tuberculosis TrxB2-DUC mutant treated or not with atc and DTT

ABSTRACT: M. tuberculosis thioredoxin reductase (TrxB2) is essential for bacterial survival in vitro and in vivo. To gain insight into the pathways dependent on TrxB2, we compared the mRNA profiles of TrxB2-DUC mutant in the presence and absence of atc and DTT. We grew bacteria in 7H9 medium to an OD of 0.5~0.6. We then added atc to a final concentration of 800 ng/ml and DTT to a final concentration of 2 mM. Samples were collected 24 hr after treatment.

ORGANISM(S): Mycobacterium tuberculosis H37Rv

SUBMITTER: Kan Lin 

PROVIDER: E-GEOD-78894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress