Expression data from melanosis coli (MC)

ABSTRACT: There is still a big debate about the correlation between melanosis coli (MC) and carcinoma. We used HTA2.0 to investigate the expression changes of lncRNAs and mRNAs in human colonic mucosa with or without MC and try to investigate MC from gene aspect, eventually to demonstrate whether there’s a certain correlation between MC and carcinoma. GeneChip® Human Transcriptome Array 2.0 (HTA 2.0) microarrays were adopted. The expression profile of lncRNAs and mRNA were tested in five colon tissue biopsy specimen of MC patients and five demographically-matched controls. This study recruited a total of five MC patients and five coupled matched controls. All specimens were obtained from colonoscopy. The fresh specimens of colon tissues form MC patients and control patients were washed with RNAas

ORGANISM(S): Homo sapiens

SUBMITTER: Shiyi Wang 

PROVIDER: E-GEOD-78933 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress