LET-dependent change in rice gene expression profile after heavy-ion beam irradiation [time]

ABSTRACT: Linear energy transfer (LET) is an important factor affecting several aspects of the irradiation effect, e.g. cell survival and mutation frequency, making the heavy-ion beam an effective mutagen. To study the mechanisms behind LET-dependent effects, expression profiling was performed after heavy-ion beam irradiation of imbibed rice seeds. Array-based experiments at three time points (0.5, 1, 2 h after the irradiation) revealed that the number of up- or down-regulated genes was highest 2 h after irradiation. Array-based experiments with four different LETs at 2 h after irradiation identified LET-independent regulated genes that were up/down-regulated regardless of the value of LET; LET-dependently regulated genes, whose expression level increased with the rise of LET value, were also identi

ORGANISM(S): Oryza sativa

SUBMITTER: Kotaro Ishii 

PROVIDER: E-GEOD-78997 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress