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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression profiling of blood in hidradenitis suppurativa

ABSTRACT: To acquire a better understanding of the molecular pathogenesis of hidradenitis suppurativa (HS), we performed mRNA microarray studies to compare whole blood gene expression of HS patients to that of healthy normal subjects. No significant difference was observed in whole blood mRNA expression between HS patients and healthy normal control. Whole blood samples were collected from patients with hidradenitis (n=16) at baseline and healthy normal subjects (n=10) for RNA extraction and microarray analysis.

ORGANISM(S): Homo sapiens

SUBMITTER: K Li

PROVIDER: E-GEOD-79149 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling of skin and blood in hidradenitis suppurativa.

Blok J L JL Li K K Brodmerkel C C Jonkman M F MF Horváth B B

The British journal of dermatology 20160302 6

PMID: 26707687

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Gene expression profiling of blood in hidradenitis suppurativa

Project description:To acquire a better understanding of the molecular pathogenesis of hidradenitis suppurativa (HS), we performed mRNA microarray studies to compare whole blood gene expression of HS patients to that of healthy normal subjects. No significant difference was observed in whole blood mRNA expression between HS patients and healthy normal control.

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Gene expression profiling of skin in hidradenitis suppurativa

Project description:To acquire a better understanding of the molecular pathogenesis of HS, we performed mRNA microarray studies to compare gene expression in lesional skin to healthy skin of HS patients. A significant difference was observed in mRNA expression between lesional and clinically healthy skin of HS patients. Skin biopsy samples (n=30, LS: lesion, NL: non-lesion) were collected at baseline from patients with hidradenitis for RNA extraction and microarray analysis.

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