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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Regular physical activity followed by detraining increases the sensitivity of global gene expression to acute exercise stress

ABSTRACT: To determine the influence of a previous physcial activity period (e.g., exercise) on global gene expression, we compared differential expression in sedentary (SED) and detrained (DETR) rats relative to trained (TR) rats with regular access to physcial activity. TR and DETR rats had voluntary access to caged running wheels for 8 and 4 weeks, respectively. DETR rats were moved to sedentary conditions (normal cage activity) for another 4 weeks. SED rats experienced 8 weeks of normal caged activity; n=8 per group. At the end of each group's respective 8 weeks, all rats underwent 1 hr of moderate of acute exercise stress (e.g., forced wheel running at a speed of 20 m/min). Soleus muscles were harvested 24h post-running.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Jon-Philippe Hyatt

PROVIDER: E-GEOD-79894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Regular physical activity followed by detraining increases the sensitivity of global gene expression to acute exercise stress

Project description:To determine the influence of a previous physcial activity period (e.g., exercise) on global gene expression, we compared differential expression in sedentary (SED) and detrained (DETR) rats relative to trained (TR) rats with regular access to physcial activity.

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2024-02-29 | PXD040785 | Pride

Gene expression data from 16-month and 3-month old male rats, with three different levels of activity over the life span: sedentary, twice weekly physical activity, regular running wheel exercise.

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RNA-Seq of effects of exercise-induced Extracellular Vesicles on an F344 rat (Rattus norvegicus) model of forced running wheel exercise

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2015-12-09 | E-GEOD-75781 | biostudies-arrayexpress

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