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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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CD54âNOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer

ABSTRACT: Using high sensitive ArrayStar Human, we detected differentially expressed genes and circRNAs, these part of data is the aberrent expressed genes. 12 Male NOD/SCID mice were obtained from the Animal Center of the Chinese Academy of Medical Science (Beijing, China). For xenograft generation, 1Ã10^6 LNCaP cells were subcutaneously injected into the backs of NOD/SCID mice (n=24). When tumors reached a diameter of 5 mm after 3 d, mice were randomly divided into two groups without castration (12 per group). Mice in the treatment group were administered with cisplatin at a dose of 5 mg/kg every 3 d for 30 d. Mice in the control group were treated with vehicle PBS. Tumors were taken out for microarray assay after 30 d.

ORGANISM(S): Homo sapiens

SUBMITTER: Guoqing Wang

PROVIDER: E-GEOD-80209 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression data from LNCaP cells

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