Transcription profiling of mouse mammary gland at key stages in development

ABSTRACT: The transition from pregnancy to lactation is a critical event in the survival of the newborn since all the nutrient requirements of the infant are provided by milk. While milk contains numerous components, including proteins, that aid in maintaining the health of the infant, lactose and milk fat represent the critical energy providing elements of milk. Much of the research to date on mammary epithelial differentiation has focused upon expression of milk protein genes, providing a somewhat distorted view of alveolar differentiation and secretory activation. While expression of milk protein genes increases during pregnancy and at secretory activation, the genes whose expression is more tightly regulated at this transition are those that regulate lipid biosynthesis. The sterol regulatory ele

ORGANISM(S): Mus musculus

SUBMITTER: Michael Rudolph 

PROVIDER: E-GEOD-8191 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress