Transcription profiling of mouse C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression

ABSTRACT: Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this study provide insights into the effects of increasing integirn alpha7 expression on muscle cells and possible side effects associate with enhancing integrin alpha7 in muscle cells. Experiment Overall Design: Triplicate biological smaples for each condition(induced and non-induced) C2C12 myoblast were used.

ORGANISM(S): Mus musculus

SUBMITTER: Jianming Liu 

PROVIDER: E-GEOD-8312 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress