Developmental transcriptomes of the two sexes in Caenorhabditis elegans during sexual maturation

ABSTRACT: We compare whole-animal RNA-seq transcriptomes for C. elegans males and hermaphrodites from the late L3 larval stage to young adulthood. During this interval, male sexual structures develop, including extensive neurogenesis and synaptogenesis that nearly doubles the size of the nervous system. Previous genome-wide expression studies in C. elegans have usually focused on only one sex – the hermaphrodite, and there are a relatively large number of predicted genes that still remain without meaningful annotation. In the present study, differential expression analysis of the RNA-seq data revealed 1,751 genes expressed at a higher level in the male. By differential expression analysis, unbiased gene correlation analysis, and a guilt-by-association approach, we identified new transcription fact

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Byunghyuk Kim 

PROVIDER: E-GEOD-83216 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress