Effect of GDF11 on RANKL-induced osteoclastogenesis

ABSTRACT: GDF11 treatment leads to bone loss in mice and strongly stimulates RANKL-induced osteoclastogenesis of bone marrow-“derived macrophages (BMMs) in vitro. We used microarrays to identified distinct classes of up-regulated genes in BMMs after GDF11 treatment. Mouse BMMs were treated with or without GDF11 for RNA extraction and and hybridization on Affymetrix microarrays

ORGANISM(S): Mus musculus

SUBMITTER: Quan Yuan 

PROVIDER: E-GEOD-84609 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress